Stephen Klasko, MD
Transformative Leader & Advocate for Revolution in Healthcare, Education and Health Disparities; Former CEO of Thomas Jefferson University and Jefferson Health
Biography
Dr. Stephen K. Klasko is a visionary healthcare leader bridging traditional academic medicine with generative AI and digital transformation. As a former health system CEO and university president, he led Thomas Jefferson University & Jefferson Health through transformative growth from $1.5 billion to $10 billion and pioneered the merger between a health science university and a nationally ranked design/architecture university. Currently serving as Executive in Residence at General Catalyst, he leads companies focused on healthcare workforce transformation while also working with Sheba Medical Center and Abundant Venture Partners. His leadership extends to board positions at NYSE's Teleflex (Lead Independent Director), Nasdaq's DocGo (board chair), and numerous innovative startups including Globo, Applied Cognition, CraniUs, Paradigm, Oova, and Agentis. Dr. Klasko also holds a Presidential Appointment to the National Board of Education Sciences and previously served as Dean of two medical colleges, University of South Florida and Drexel University College of Medicine. A prolific author and thought leader, Dr. Klasko's publications include his latest book with Ryan Donohue, "Patient No Longer: How YOU Can Lead the Consumer Revolution in Healthcare" (March 2025), "Feelin' Alright: How the Message in the Music Can Make Healthcare Healthier" (2023), "UnHealthcare: A Manifesto for Health Assurance" with Hemant Taneja (2021), and several other influential works, including a parody children's book, "Bless This Mess: A Picture Story of Healthcare in America: Do Not Read This at Bedtime, It's scary." His visionary approach has earned him recognition as #2 in Modern Healthcare's "100 Most Influential People in Healthcare," #21 in Fast Company's "100 Most Creative People in Business," "distinguished fellow at the World Economic Forum," "Founders Award at the National Academy of Inventors" and numerous other accolades. Dr. Klasko holds an MD from Hahnemann University and an MBA from the Wharton School at the University of Pennsylvania, an honorary doctorate from Fairleigh Dickinson University and is completing his law degree at University of New Hampshire concentrating on the unintended legal consequences of AI in health. He also is an active DJ in Miami. He started his career as a working radio DJ and still spins tunes with very different music from Miami to San Francisco.
Speech Topics
Healthcare at Any Address.
How shifting the locus of care to the home gives people control of their own health, and allows clinicians to engage families and even communities in keeping people healthy.
Why The Digital Revolution Cannot Simply Make the Wealthy Healthier.
Technology gives us an unprecedented opportunity to bridge the divides that threaten our society – if we have the determination to make it happen.
Health Assurance in 2031: From COVID to Consumerism
This talk speaks to payor-provider alignment in the MA space. It’s March, 2032. A mutant strain of an RNA encapsulated virus has been afflicting people in Australia. Of course, people old enough to remember, especially healthcare workers, the dark days of early 2020 and the COVID 19 crisis immediately panicked….for a second…and then they smiled. Because they knew healthcare had evolved from a broken, fragmented, expensive, inequitable “sick care” system to a “health assurance” system where there is payor-provider alignment and much of a patient's care happens at home. We are witnessing healthcare’s “Amazon moment.” If you are a provider and think you’re going back to a business model solely based on hospital revenue and not relevant to people who want care at home, you will be out of business. If you are an insurer and think you can just be the middle man between the hospital and the patient, you’ll be irrelevant. If hospitals believe that innovation can just be this cute little thing that they do in the background, but the real business is getting “heads in beds” they will never recover from the pandemic of 2020-2022 losses. This keynote will highlight several post pandemic strategies, including: 1) New creative partnerships between community partners, health systems and payors as we move from “sick care” to “health assurance.” The fragmentation between payors and providers was replaced by a "radical collaboration through vehicles such as Medicare Advantage 2) The fastest growing demographic, seniors, redefined health provision through demanding and receiving healthcare in an understandable and connected manner. We will cite the results of the first "patient owned, primary care driven health system in a large senior community." 3) How providers handle data today will make or break patient trust in the future. 4) Technology can start to address health disparities but it must be applied strategically. 5) The most prized skills for physicians will be empathy, communication and self-awareness in the digital age. 6) How population health, predictive analytics and social determinants move from philosophy to the mainstream of clinical care, payment models and medical education.
Is There an Avatar in the House?
The revolution that needs to happen in medical education and training to ensure that machine learning and computers become members of teams where the humans get to focus on the human questions.
The Courage to Change: A Soundtrack (for Leadership)
If there’s anything I’ve learned in 40 years as a dean, CEO and president, it’s that we each need our own toolbox for an optimistic future. I recently retired as president of Thomas Jefferson University and CEO of Jefferson Health to pursue my passion for using technology to reduce costs and address health disparities. As I step away from a career as dean of two medical schools, CEO of three academic health systems and president of a university, these are my reflections on that toolbox for optimism. My message to you: Make sure your toolbox is full. My toolbox has always included music. I’ve been a DJ for 50 years and a doctor for 40 years, so every Friday during the pandemic, I sent a playlist to our employees to remind them that art and music and humanity are still alive and well, despite the tough times each of us was experiencing. What I said repeatedly to my employees: We should listen to “The Message in the Music” (the O’Jays, lyrics by Philly’s own Kenny Gamble and Leon Huff). When I left Thomas Jefferson University and Jefferson Health, I gave an interview to the Philadelphia Business Journal based on songs in my toolbox, that I want to share with my colleagues and friends in the industry.
The Courage to Change: Lessons From the AI Revolution for Educating Human Beings
Unintended consequences are not unintended if you know they are going to happen. Stephen K. Klasko, M.D., M.B.A., is the former President of Thomas Jefferson University and CEO of Jefferson Health who is now an executive at the country's leading generative AI venture capital firm and is on President Biden's National Board of Education Sciences. He has advocated for transformations in healthcare and education that encourage responsible AI and embrace a radical collaboration between human, computer and generative AI in educating the next generation of Americans incorporating the best in human design thinking and creativity with the amazing advances in large language model education sciences. He will discuss the good, bad and ugly of these new technologies as well as his success in transforming the selection, education and diversity of students in a variety of fields.
What Will Healthcare Look Like in 2030
Videos
Testimonials
"“I would like to thank you once again for participating at our 2018 AMS Phoenix Conference. Your keynote was thought provoking and engaging, and your participation in the closing panel of the event was very positively received by the conference participants, and there was extremely positive feedback on social media.”"
"“As the opening speaker for our annual conference, Dr. Stephen Klasko needed to set the bar high for our three-day event—and he did not disappoint. His use of humor and pop culture references had the audience completely engaged, and his clear message and thoughtful presentation provided valuable insight for the attendees to bring back to their companies. Dr. Klasko was everything you want in a Keynote speaker and more. Simply put, he was exceptional.”"
"“Dear Dr. Klasko, I want to thank you for serving as the keynote speaker for our Texas Covered Conference + Expo last week. Your presentation on the future of health care was entertaining (I always appreciate a Star Wars reference) and informative, and it really set high expectations for the entire event. We could not have asked for a better speaker. Thank you so much for coming and being exceptional.”"
Frequently Asked Questions
How can I check Stephen Klasko, MD's availability or request a quote?
You can inquire about Stephen Klasko, MD's availability or get a customized quote by contacting Key Speakers directly. Our team will help you determine fit, logistics, and budget options for your upcoming event.What is Stephen Klasko, MD's speaking fee?
The typical range for Stephen Klasko, MD's speaking fee is $14,000–$25,000. The low end of the fee range represents their standard virtual fee. The high end of the fee range represents their standard fee for a US-based in-person speaking engagement. Appearances which require an extended schedule of activities or international travel will possibly exceed this fee range. Speaker fees update frequently. To receive a personalized quote for Stephen Klasko, MD to speak at your event, please consult with a Key Speakers advisor for up to date information and assistance.What factors influence the speaker's fee?
Other factors that influence a keynote speaker's fee include their reputation, expertise, demand, experience, duration of the presentation, travel requirements for the event location, and any additional services, activities or customization options they offer.Are travel expenses included in the speaker's fee?
Travel expenses are typically not included in the listed speaker's fee and are quoted separately. If the speaker needs to travel internationally, fees will be higher. These expenses may include airfare, accommodation, ground transportation at home and in the event city, and meals. We can provide more detailed information about travel expenses and arrangements once you've selected a speaker.How do I book Stephen Klasko, MD for my event?
The speaker booking process typically involves the following steps: contact Key Speakers to confirm Stephen Klasko, MD's availability, fees, and any unique requirements (we can also help negotiate fees and terms); submit a firm offer to extend the invite to your speaker, with the details used to create an agreement once the speaker accepts; coordinate and finalize the terms of the booking, including contract terms and conditions; and confirm the booking by signing the contract and making the necessary payments.What types of events do keynote speakers typically speak at?
Keynote speakers can speak at a wide range of events, virtual or in person, including conferences, corporate meetings, industry conventions, seminars, workshops, fundraising galas, educational programs, and other special occasions where an inspirational or informative address is desired.How do I select the right keynote speaker for my event?
When selecting a keynote speaker, consider the following factors: the speaker's expertise and knowledge relevant to your event's theme or industry; their speaking style, ability to engage the audience, and deliver impactful messages; past client testimonials, reviews, or references; and the speaker's availability and fee within your budget.What are the payment terms and conditions?
A deposit is required upon signing the contract, with the remaining balance due 2–4 weeks before the event. If the event is taking place within 30 days, the full balance is due upon signing.How far in advance should I book a keynote speaker?
It is generally advisable to book a keynote speaker as early as possible, especially if you have a specific speaker in mind or if your event is during a peak season holiday. Ideally, booking a speaker three to six months in advance can increase the chances of securing your desired speaker.Can you help me with the logistics and technical requirements for the speaker's presentation?
Yes, we can assist you with the logistics and technical requirements for the speaker's presentation. We stay actively involved during pre-event planning to coordinate with you and ensure that the necessary audiovisual equipment, staging, lighting, and other technical aspects are in place for a successful presentation.Are there any special requirements or accommodations that need to be considered for the speaker?
Keynote speakers may have specific requirements or accommodations that need to be considered, such as travel arrangements, accommodation preferences, dietary restrictions, or accessibility needs. Some speakers have a performance rider we include in the contract, others have minimal requirements.Do keynote speakers offer customization options for their presentations?
Yes, many keynote speakers offer customization options for their presentations. They can tailor their content, examples, or case studies to align with your event's theme, industry, or specific audience. Discuss your customization needs with us so we can guide you accordingly.Can the speaker participate in pre-event activities such as panel discussions or Q&A sessions?
Some keynote speakers are open to participating in pre-event activities such as panel discussions, Q&A sessions, or meet-and-greet sessions. Please share your specific requirements with us during the firm offer phase, so we can work on getting you everything you need.How long is a typical keynote speech?
The duration of a standard keynote speech can vary depending on the speaker and the event's schedule. Typically, keynote speeches range from 30 minutes to 90 minutes, including any Q&A sessions or interactive elements. Some speakers can accommodate half or full day sessions and extended keynotes. Discuss the desired duration with your representative to determine the appropriate length for participation.Can I provide feedback or reviews about the speaker's performance?
Yes, we encourage and appreciate feedback about the speaker's performance as well as our services. You can share your feedback via email after the event, or via our survey feedback form. Your feedback can help us improve our services and assist other clients in making informed decisions.Are there any discounts or special offers available for booking multiple speakers or multiple events?
Often, yes. It's worth inquiring about such possibilities with your Key Speakers representative to explore any available cost-savings options.Why book Stephen Klasko, MD through Key Speakers?
We provide a comprehensive service that takes the guesswork out of hiring a speaker — from speaker selection to logistics to post-event feedback. We know you have lots of responsibilities on top of finding and coordinating event speakers, so having a committed and proactive partner on your side that is an expert with the talent booking process is crucial. Every time you book a speaker with Key, your dedicated events manager will support you throughout the entire planning process. We help you negotiate contractual details such as speaker fees and travel terms so that you end up with the most favorable deal. With our highly communicative booking and proposal model, you'll never be left in the dark with the status of your speaker. To put it simply, Key Speakers is your one-stop resource for finding, booking and managing speakers for your event.
Speakers Like Stephen Klasko, MD

Daniel Kraft, MD
Daniel Kraft is a Stanford and Harvard trained physician, scientist, entrepreneur, inventor and innovator who speaks on how rapidly developing technologies are and will impact the future of healthcare and medicine.
Fee Range: $21,000–$30,000
Travels From: CA

Lynda Chin, MD
An elected member of the National Academy of Medicine, Dr. Chin is a renowned cancer genomic scientist and a leader in the application of analytical technologies, AI/ML, and big data in medicine. Her groundbreaking work synthesizing terabyte-scale datasets in genomics and oncology research has opened new frontiers in digital medicine. Dr. Chin founded Apricity Health, a next-generation precision medicine company to harness patient data and clinical expertise to develop better drugs and deliver better care for cancer patients.
Fee Range: $8,000–$15,000
Travels From: TX
Check Stephen Klasko, MD’s Availability
Tell us about your event and we’ll be in touch shortly.









