Matthew Zachary
Healthcare Provocateur, Award-Winning Podcast Influencer, and The People’s Voice in Healthcare
Biography
Matthew Zachary defines himself as a Health Experience Officer. With a 20+ year career in entertainment, advertising, marketing, nonprofit, digital health, public policy, life sciences, and broadcast media, Matthew is considered one of the industry's most respected, influential, and visionary voices. He is passionate about putting the patient at the center of every conversation. Why? Because he is one. Diagnosed as a college senior with brain cancer, Matthew wasn't sure he'd make his next birthday. That was 27 years ago. Matthew has been called "The Podfather," "The Howard Stern," and "The People's Voice" in healthcare. He has been profiled by The CBS Evening News, TIME Magazine, People Magazine, Newsweek, STAT, The New York Times, The Wall Street Journal, The Washington Post, The Atlantic, MTV, and others. Matthew is a recovering ad agency veteran and a Founding Advisor to Google Health. As the Founder of the award-winning nonprofit organization Stupid Cancer, he birthed the Young Adult Cancer Movement, which improved the lives of millions of patients in their teens, 20s, and 30s. Currently, he is the CEO and Co-Founder of OffScrip Health—a leading digital health media platform—where he hosts "Out of Patients with Matthew Zachary," one of the most prestigious, influential, and coveted interview shows in the sector, and a TOP-10 healthcare podcast. He lives with his wife and twins in Brooklyn, NY.
Speech Topics
Patient v Consumer
Trust and empathy are central aspects of improving healthcare. While their importance is receiving recognition, systemic risk aversion and groupthink complacency have impeded implementation. The result is an increasing erosion of trust between patients and "the system," especially in healthcare marketing and communications. The country's topmost honest and ethical professions are doctors, nurses, grade-school teachers, and pharmacists (Gallup,) and yet, 91% of all patients believe industry prioritizes people over profits (Harris). Consumer brands understand trust and empathy as social science guides their tactics with end-user consumers. In healthcare, the provider is the end-user. What if it were possible for healthcare communications to utilize the same tactics as consumer brands? In this talk, Matthew sheds light on how we might innovate our way out of this by learning from CPG use cases, nonprofit communications, digital health solutions, shifting trends in consumer media consumption, shared accountability, and increased federal protections.
Permission To Be Pissed
Ten years after his brain cancer diagnosis, in 2007, Matthew Zachary founded Stupid Cancer out of his second bedroom with a dollar and a dream. Broadband and smartphones were years away, this so-called Facebook raised our eyebrows, and "Young Adult Cancer" did not exist in the lexicon of advocates, researchers, or policymakers. The next generation of cancer patients looked to the past for cues to channel their anger toward action and force the hands of government and medicine to enact critical policy and practice reforms. The Young Adult Cancer Movement was born. In this talk, Matthew takes audiences on a journey back in time to the origins of patient movements that brought us to today's narrative. Now in his 27th year in remission, Matthew shares his personal story and lessons learned by way of his hodgepodge lived experiences, including but not limited to: concert pianist, Madison Avenue exec, Google advisor, nonprofit leader, digital health startup guy, patient advocate, fertility rights activist, futurist, GenX spokesperson, and 80's pop culture nerd.
Videos
Frequently Asked Questions
How can I check Matthew Zachary's availability or request a quote?
You can inquire about Matthew Zachary's availability or get a customized quote by contacting Key Speakers directly. Our team will help you determine fit, logistics, and budget options for your upcoming event.What is Matthew Zachary's speaking fee?
The typical range for Matthew Zachary's speaking fee is $18,000–$40,000. The low end of the fee range represents their standard virtual fee. The high end of the fee range represents their standard fee for a US-based in-person speaking engagement. Appearances which require an extended schedule of activities or international travel will possibly exceed this fee range. Speaker fees update frequently. To receive a personalized quote for Matthew Zachary to speak at your event, please consult with a Key Speakers advisor for up to date information and assistance.What factors influence the speaker's fee?
Other factors that influence a keynote speaker's fee include their reputation, expertise, demand, experience, duration of the presentation, travel requirements for the event location, and any additional services, activities or customization options they offer.Are travel expenses included in the speaker's fee?
Travel expenses are typically not included in the listed speaker's fee and are quoted separately. If the speaker needs to travel internationally, fees will be higher. These expenses may include airfare, accommodation, ground transportation at home and in the event city, and meals. We can provide more detailed information about travel expenses and arrangements once you've selected a speaker.How do I book Matthew Zachary for my event?
The speaker booking process typically involves the following steps: contact Key Speakers to confirm Matthew Zachary's availability, fees, and any unique requirements (we can also help negotiate fees and terms); submit a firm offer to extend the invite to your speaker, with the details used to create an agreement once the speaker accepts; coordinate and finalize the terms of the booking, including contract terms and conditions; and confirm the booking by signing the contract and making the necessary payments.What types of events do keynote speakers typically speak at?
Keynote speakers can speak at a wide range of events, virtual or in person, including conferences, corporate meetings, industry conventions, seminars, workshops, fundraising galas, educational programs, and other special occasions where an inspirational or informative address is desired.How do I select the right keynote speaker for my event?
When selecting a keynote speaker, consider the following factors: the speaker's expertise and knowledge relevant to your event's theme or industry; their speaking style, ability to engage the audience, and deliver impactful messages; past client testimonials, reviews, or references; and the speaker's availability and fee within your budget.What are the payment terms and conditions?
A deposit is required upon signing the contract, with the remaining balance due 2–4 weeks before the event. If the event is taking place within 30 days, the full balance is due upon signing.How far in advance should I book a keynote speaker?
It is generally advisable to book a keynote speaker as early as possible, especially if you have a specific speaker in mind or if your event is during a peak season holiday. Ideally, booking a speaker three to six months in advance can increase the chances of securing your desired speaker.Can you help me with the logistics and technical requirements for the speaker's presentation?
Yes, we can assist you with the logistics and technical requirements for the speaker's presentation. We stay actively involved during pre-event planning to coordinate with you and ensure that the necessary audiovisual equipment, staging, lighting, and other technical aspects are in place for a successful presentation.Are there any special requirements or accommodations that need to be considered for the speaker?
Keynote speakers may have specific requirements or accommodations that need to be considered, such as travel arrangements, accommodation preferences, dietary restrictions, or accessibility needs. Some speakers have a performance rider we include in the contract, others have minimal requirements.Do keynote speakers offer customization options for their presentations?
Yes, many keynote speakers offer customization options for their presentations. They can tailor their content, examples, or case studies to align with your event's theme, industry, or specific audience. Discuss your customization needs with us so we can guide you accordingly.Can the speaker participate in pre-event activities such as panel discussions or Q&A sessions?
Some keynote speakers are open to participating in pre-event activities such as panel discussions, Q&A sessions, or meet-and-greet sessions. Please share your specific requirements with us during the firm offer phase, so we can work on getting you everything you need.How long is a typical keynote speech?
The duration of a standard keynote speech can vary depending on the speaker and the event's schedule. Typically, keynote speeches range from 30 minutes to 90 minutes, including any Q&A sessions or interactive elements. Some speakers can accommodate half or full day sessions and extended keynotes. Discuss the desired duration with your representative to determine the appropriate length for participation.Can I provide feedback or reviews about the speaker's performance?
Yes, we encourage and appreciate feedback about the speaker's performance as well as our services. You can share your feedback via email after the event, or via our survey feedback form. Your feedback can help us improve our services and assist other clients in making informed decisions.Are there any discounts or special offers available for booking multiple speakers or multiple events?
Often, yes. It's worth inquiring about such possibilities with your Key Speakers representative to explore any available cost-savings options.Why book Matthew Zachary through Key Speakers?
We provide a comprehensive service that takes the guesswork out of hiring a speaker — from speaker selection to logistics to post-event feedback. We know you have lots of responsibilities on top of finding and coordinating event speakers, so having a committed and proactive partner on your side that is an expert with the talent booking process is crucial. Every time you book a speaker with Key, your dedicated events manager will support you throughout the entire planning process. We help you negotiate contractual details such as speaker fees and travel terms so that you end up with the most favorable deal. With our highly communicative booking and proposal model, you'll never be left in the dark with the status of your speaker. To put it simply, Key Speakers is your one-stop resource for finding, booking and managing speakers for your event.
Speakers Like Matthew Zachary

Myrtle Potter
Myrtle Potter is a best selling author and one of America’s foremost and accomplished healthcare leaders and experts. Myrtle has dedicated three decades to serving the healthcare needs of patients and consumers through her leadership of some of America’s most successful global healthcare companies. She was a vice president, at Merck, president at Bristol-Myers Squibb and later was named president and chief operating officer of Genentech, the world’s biotechnology powerhouse, committed to developing powerful therapies for cancer, autoimmune diseases most successful biotechnology company. Myrtle Potter champions the right for people to have control over their unique, personal journey through the healthcare system.
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Stephen Klasko, MD
• Executive in Residence, General Catalyst • Global Innovation Ambassador, Sheba Medical Center, Israel • Distinguished Fellow, World Economic Forum • Former President and CEO, Thomas Jefferson University and Jefferson Health •Appointed by President Biden with senate confirmation to the National Board of Education Sciences. •Started his career as DJ “Stevie Kent”
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Lynda Chin, MD
An elected member of the National Academy of Medicine, Dr. Chin is a renowned cancer genomic scientist and a leader in the application of analytical technologies, AI/ML, and big data in medicine. Her groundbreaking work synthesizing terabyte-scale datasets in genomics and oncology research has opened new frontiers in digital medicine. Dr. Chin founded Apricity Health, a next-generation precision medicine company to harness patient data and clinical expertise to develop better drugs and deliver better care for cancer patients.
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Nicole Malachowski
Colonel Nicole Malachowski is a top keynote speaker, former White House advisor, and the first female Thunderbird pilot. An inductee into the Women in Aviation International Pioneer Hall of Fame and the National Women’s Hall of Fame, Malachowski brings her experience to the stage and holds audiences spellbound with an easygoing authenticity of someone who’s achieved greatness. Since a chronic tick-borne illness prompted her medical retirement from the military, she has turned her fiery spirit to advocating support and research for tick-borne diseases, in addition to quickly building a reputation as a sensational and effective speaker on the topics of achievement, overcoming adversity, and rocking the status quo.
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